2. Metabolic Enzyme/Protease
  3. Glutaminase
  4. TG-2-IN-1

TG-2-IN-1 (Compound D003) is a transglutaminase-2 (TGM-2) inhibitor. TG-2-IN-1 can be used for the research of myopia.

For research use only. We do not sell to patients.

TG-2-IN-1 Chemical Structure

TG-2-IN-1 Chemical Structure

CAS No. : 135273-74-4

Size Price Stock Quantity
5 mg USD 100 In-stock
10 mg USD 170 In-stock
25 mg USD 360 In-stock
50 mg USD 580 In-stock
100 mg USD 920 In-stock
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500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

TG-2-IN-1 Related Antibodies

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Description

TG-2-IN-1 (Compound D003) is a transglutaminase-2 (TGM-2) inhibitor. TG-2-IN-1 can be used for the research of myopia[1].

Molecular Weight

220.72

Formula

C8H13ClN2OS
CAS No.
Appearance

Solid

Color

Off-white to light brown

SMILES

CC(CSC1=[N+](C)C=CN1C)=O.[Cl-]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*The compound is unstable in solutions, freshly prepared is recommended.

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (453.06 mM; Need ultrasonic)

DMSO : 25 mg/mL (113.27 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.5306 mL 22.6531 mL 45.3063 mL
5 mM 0.9061 mL 4.5306 mL 9.0613 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / H2O 1 mM 4.5306 mL 22.6531 mL 45.3063 mL 113.2657 mL
5 mM 0.9061 mL 4.5306 mL 9.0613 mL 22.6531 mL
10 mM 0.4531 mL 2.2653 mL 4.5306 mL 11.3266 mL
15 mM 0.3020 mL 1.5102 mL 3.0204 mL 7.5510 mL
20 mM 0.2265 mL 1.1327 mL 2.2653 mL 5.6633 mL
25 mM 0.1812 mL 0.9061 mL 1.8123 mL 4.5306 mL
30 mM 0.1510 mL 0.7551 mL 1.5102 mL 3.7755 mL
40 mM 0.1133 mL 0.5663 mL 1.1327 mL 2.8316 mL
50 mM 0.0906 mL 0.4531 mL 0.9061 mL 2.2653 mL
60 mM 0.0755 mL 0.3776 mL 0.7551 mL 1.8878 mL
80 mM 0.0566 mL 0.2832 mL 0.5663 mL 1.4158 mL
100 mM 0.0453 mL 0.2265 mL 0.4531 mL 1.1327 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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TG-2-IN-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TG-2-IN-1135273-74-4Glutaminasetransglutaminase-2TGM-2 inhibitormyopiaInhibitorinhibitorinhibit

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