Thiol-C2-PEG2-OH
Based on 1 Customer Validation
Thiol-C2-PEG2-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: 97.83%
- CAS No.: 56282-36-1
- Formula: C6H14O3S
- Molecular Weight:166.24
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Storage:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All PROTAC Linkers Isoforms
More
Biological Activity
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 56282-36-1
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Appearance Liquid
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Molecular Weight 166.24
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Formula C6H14O3S
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Color Colorless to light yellow
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SMILES
SCCOCCOCCO
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
DMSO : ≥ 100 mg/mL (601.54 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (265 KB)
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SDS (701 KB)
- English - EN (701 KB)
- Français - FR (701 KB)
- Deutsch - DE (701 KB)
- Norwegian - NO (701 KB)
- Español - ES (701 KB)
- Swedish - SV (701 KB)
- Italian - IT (701 KB)
- Portuguese - PT (701 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 6.0154 mL | 30.0770 mL | 60.1540 mL | 150.3850 mL |
| 5 mM | 1.2031 mL | 6.0154 mL | 12.0308 mL | 30.0770 mL | |
| 10 mM | 0.6015 mL | 3.0077 mL | 6.0154 mL | 15.0385 mL | |
| 15 mM | 0.4010 mL | 2.0051 mL | 4.0103 mL | 10.0257 mL | |
| 20 mM | 0.3008 mL | 1.5038 mL | 3.0077 mL | 7.5192 mL | |
| 25 mM | 0.2406 mL | 1.2031 mL | 2.4062 mL | 6.0154 mL | |
| 30 mM | 0.2005 mL | 1.0026 mL | 2.0051 mL | 5.0128 mL | |
| 40 mM | 0.1504 mL | 0.7519 mL | 1.5038 mL | 3.7596 mL | |
| 50 mM | 0.1203 mL | 0.6015 mL | 1.2031 mL | 3.0077 mL | |
| 60 mM | 0.1003 mL | 0.5013 mL | 1.0026 mL | 2.5064 mL | |
| 80 mM | 0.0752 mL | 0.3760 mL | 0.7519 mL | 1.8798 mL | |
| 100 mM | 0.0602 mL | 0.3008 mL | 0.6015 mL | 1.5038 mL |
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