1. Metabolic Enzyme/Protease
  2. Thrombin
  3. Thrombin Inhibitor 2

Thrombin Inhibitor 2 is a small molecule direct thrombin inhibitor, extracted from US8541580B2. Thrombin Inhibitor 2 has antithrombotic activity.

For research use only. We do not sell to patients.

Thrombin Inhibitor 2 Chemical Structure

Thrombin Inhibitor 2 Chemical Structure

CAS No. : 312904-62-4

Size Price Stock Quantity
5 mg USD 580 In-stock
10 mg USD 1050 In-stock
25 mg USD 2250 In-stock
50 mg USD 3600 In-stock
100 mg USD 5800 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

Thrombin Inhibitor 2 is a small molecule direct thrombin inhibitor, extracted from US8541580B2. Thrombin Inhibitor 2 has antithrombotic activity[1].

Molecular Weight

452.82

Formula

C19H16ClF3N6O2

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(NCC1=NC=CC=C1F)CN2C(C(NCC(F)(F)C3=NC=CC=C3)=NC=C2Cl)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (110.42 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2084 mL 11.0419 mL 22.0838 mL
5 mM 0.4417 mL 2.2084 mL 4.4168 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.2084 mL 11.0419 mL 22.0838 mL 55.2096 mL
5 mM 0.4417 mL 2.2084 mL 4.4168 mL 11.0419 mL
10 mM 0.2208 mL 1.1042 mL 2.2084 mL 5.5210 mL
15 mM 0.1472 mL 0.7361 mL 1.4723 mL 3.6806 mL
20 mM 0.1104 mL 0.5521 mL 1.1042 mL 2.7605 mL
25 mM 0.0883 mL 0.4417 mL 0.8834 mL 2.2084 mL
30 mM 0.0736 mL 0.3681 mL 0.7361 mL 1.8403 mL
40 mM 0.0552 mL 0.2760 mL 0.5521 mL 1.3802 mL
50 mM 0.0442 mL 0.2208 mL 0.4417 mL 1.1042 mL
60 mM 0.0368 mL 0.1840 mL 0.3681 mL 0.9202 mL
80 mM 0.0276 mL 0.1380 mL 0.2760 mL 0.6901 mL
100 mM 0.0221 mL 0.1104 mL 0.2208 mL 0.5521 mL
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Thrombin Inhibitor 2 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Thrombin Inhibitor 2
Cat. No.:
HY-10217
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