Thrombin inhibitor 6
Thrombin inhibitor 6 is a potent thrombin inhibitor (IC50: 1 nM). Thrombin inhibitor 6 has the function as an anticoagulant.
For research use only. We do not sell to patients.
- CAS No.: 1628224-94-1
- Formula: C18H19ClN4O2S
- Molecular Weight:390.89
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Thrombin inhibitor 6 (compound 73) is stable when incubated with CD-1 mouse and human microsomes (Clint (mouse) = 60 μL/min/mg; Clint (human)) = 17 μL/min/mg[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Thrombin inhibitor 6 (5 mg/kg, p.o.) shows F(%) of 22.8%, AUC of 713.3 h.ng/mL and Cmax of 127 ng/mL in male CD-1 mice[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:CD-1 mice[1]
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Dosage:9 mg/kg
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Administration:Intravenous injection (i.v.)
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Result:The mice bled for 25 min following transection.
Led to 1.5-fold increase of liberated whole blood cells.
Chemical Information
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CAS No. 1628224-94-1
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Molecular Weight 390.89
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Formula C18H19ClN4O2S
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SMILES
O=C1NC=CC=C1C2=NN(C(NCC3=CC=C(Cl)S3)=C2)C(C(C)(C)C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Thrombin inhibitor 6 Related Classifications
HY-151983 Related Classifications
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