Thymol iodide 

Thymol iodide is an iodine derivative of thymol, serving as a mild preservative and fungicide. Thymol iodide is commonly used as an iodine source in the intensive culture of rotifers. Thymol iodide effectively enables Brachionus "Cayman" rotifers to reach iodine levels similar to those of copepods, and maintains a high iodine content during storage. After 28 days of intrapleural injection of Thymol iodide, it does not enhance the efficacy of inducing pleurodesis in rabbits, nor does it improve the efficacy of talc slurry pleurodesis^[1][2].

Combined administration of thymol iodide (50 mg; intrapleural injection; single dose) with 200 mg/kg talc slurry does not enhance the efficacy of pleurodesis in rabbit experiments evaluated by pleural effusion volume, gross adhesion score or microscopic fibrosis score; only 30% of the tested rabbits achieve satisfactory pleurodesis efficacy on the 14th and 28th days post-administration^[1].
Thymol iodide (0.3-25.2 g/kg feed; mixed with enrichment feed; 3 h enrichment) can efficiently enrich the iodine content of rotifers to a level comparable to that of copepods via an extremely low proportion of dietary replacement (accounting for 0.36-2.03% of the total diet), and maintains a stable iodine retention rate when stored at room temperature or low temperature for up to 18 h^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

550.21

C₂₀H₂₄I₂O₂

552-22-7

Solid

Light yellow to yellow

CC(C1=C(OI)C=C(C)C(C2=CC(C(C)C)=C(OI)C=C2C)=C1)C

Room temperature in continental US; may vary elsewhere.

• [1]. Xie C, et al. Comparisons of pleurodesis induced by talc with or without thymol iodide in rabbits. Chest. 1998;113(3):795-799.  [Content Brief]

  [2]. Srivastava A, Hamre K, Stoss J, et al. A study on enrichment of the rotifer Brachionus “Cayman” with iodine from different sources[J]. Aquaculture, 2012, 334: 82-88.