TLR7/8 agonist 8

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TLR7/8 agonist 8 (compound 24m) is a potent toll-like receptor 7/8 (TLR7/8) dual agonist, with EC50s of 27 and 12 nM for hTLR7 and hTLR8, respectively. TLR7/8 agonist 8 can improve the antitumor activity of PD-1/PD-L1 blockade.

For research use only. We do not sell to patients.

  • Purity: 98.69%
  • CAS No.: 2649170-16-9
  • Formula: C24H30N6O
  • Molecular Weight:418.53
  • Storage:
    Powder   -20°C, 3 years , 4°C, 2 years ; In solvent   -80°C, 6 months , -20°C, 1 month
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  • Chemical Information
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All Toll-like Receptor (TLR) Isoforms

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