TLR8 agonist 11
TLR8 agonist 11 is a selective human Toll-like receptor 8 (TLR8) agonist. TLR8 agonist 11 activates the hTLR8-dependent NF-κB signaling pathway. TLR8 agonist 11 can be used for the research of inflammation and immune-related diseases.
For research use only. We do not sell to patients.
- CAS No.: 1449680-12-9
- Formula: C16H18N2O
- Molecular Weight:254.33
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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hTLR8 |
NF-κB |
TLR8 agonist 11 (compound 8e) is a human TLR8-specific agonist. It exhibits lower potency than its C2-butyl analog (compound 8d) and shows biphasic NF-κB induction characteristics in TLR8-transfected HEK293 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1449680-12-9
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Molecular Weight 254.33
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Formula C16H18N2O
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SMILES
CCCCCC1=CC(C2=CC=CC=C2N=C3N)=C3O1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
TLR8 agonist 11 Related Classifications
HY-188010 Related Classifications
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