TMC-205
TMC-205 is a natural fungal metabolite with antiproliferative activity against cancer cell lines. TMC-205 is a transcriptional up-regulator of SV40 promoter.
For research use only. We do not sell to patients.
- CAS No.: 403646-00-4
- Formula: C14H13NO2
- Molecular Weight:227.26
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Endogenous Metabolite Isoforms
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Biological Activity
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Microbial Metabolite |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HCT-116 | GI50 |
68 μM
Compound: 1, TMC-205
|
Antiproliferative activity against human HCT116 cells assessed as growth inhibition after 72 hrs by MTS assay
Antiproliferative activity against human HCT116 cells assessed as growth inhibition after 72 hrs by MTS assay
|
[PMID: 25147604] |
Chemical Information
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CAS No. 403646-00-4
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Molecular Weight 227.26
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Formula C14H13NO2
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SMILES
O=C(C1=CNC2=C1C=CC(/C=C/C(C)=C)=C2)O
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Structure Classification
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Initial Source
an unidentified fungus.
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)