Totrombopag choline

(Synonyms: SB-559448 choline)

Totrombopag (SB-559448) choline is an orally effective thrombopoietin receptor (TpoR) agonist. By activating TpoR, Totrombopag choline initiates an intracellular signaling cascade mediated by JAK2 kinase and the transcription factor Stat5, a signaling process that is the primary mechanism regulating megakaryocyte growth and differentiation into platelets. Totrombopag choline can be used to study platelet production and megakaryocyte biology.

For research use only. We do not sell to patients.

  • CAS No.: 851606-62-7
  • Formula: C30H35N9O3
  • Molecular Weight:569.66
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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100 mg

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