Triclopyr

Cat. No.: HY-B2051 Purity: 99.80%: FAQs
Data Sheet SDS COA Handling Instructions

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Triclopyr, a foliar systemic herbicide and fungicide, is widely used for broadleaf and woody plant control. Triclopyr has severe toxicity.

For research use only. We do not sell to patients.

Triclopyr Chemical Structure

CAS No. : 55335-06-3

Size	Price	Stock	Quantity
100 mg	USD 25	In-stock	Estimated Time of Arrival: December 31
200 mg		Get quote
500 mg		Get quote

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Purity & Documentation
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Description

Triclopyr, a foliar systemic herbicide and fungicide, is widely used for broadleaf and woody plant control. Triclopyr has severe toxicity^[1].

In Vitro

Triclopyr (3 mM; 48 hours) treatment exhibits cytotoxicity against N2a cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay^[1]

Cell Line:	Mouse neuroblastoma (N2a) cells
Concentration:	3 mM
Incubation Time:	48 hours
Result:	Decreased significantly for cell viability (P < 0.0001) compared to the untreated N2a cells.

In Vivo

Pharmacokinetic Analysis
Triclopyr exhibits moderate half-lives (dog 25 h and monkey 6.3 h) due to plasma clearance (18 mL/h/kg, 26 mL/h/kg respectively) following oral gavage (3 male beagle dogs ;0.5 mg/kg, 5 mg/kg and 20 mg/kg) and intravenous administration (1 male rhesus monkey; 30 mg/kg) ^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	3 male beagle dogs(7.2 - 7.9 kg), 1 male rhesus monkey ^[2]
Dosage:	0.5 mg/kg, 5 mg/kg, 20 mg/kg (beagle dog); 30 mg/kg (rhesus monkey)
Administration:	Oral gavage (beagle dog); intravenous (rhesus monkey)
Result:	T_1/2s of 25 and 6.3 h for dogs and a monkey, respectively.

Molecular Weight

256.47

Formula

C₇H₄Cl₃NO₃

CAS No.

55335-06-3

Appearance

Solid

Color

White to off-white

SMILES

OC(COC1=NC(Cl)=C(Cl)C=C1Cl)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 125 mg/mL (487.39 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.8991 mL	19.4955 mL	38.9909 mL
5 mM	0.7798 mL	3.8991 mL	7.7982 mL
10 mM	0.3899 mL	1.9495 mL	3.8991 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.80%

Select Batch:

Data Sheet (248 KB) SDS (0 KB)

COA (252 KB) HNMR (246 KB) LCMS (87 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.8991 mL	19.4955 mL	38.9909 mL	97.4773 mL
	5 mM	0.7798 mL	3.8991 mL	7.7982 mL	19.4955 mL
	10 mM	0.3899 mL	1.9495 mL	3.8991 mL	9.7477 mL
	15 mM	0.2599 mL	1.2997 mL	2.5994 mL	6.4985 mL
	20 mM	0.1950 mL	0.9748 mL	1.9495 mL	4.8739 mL
	25 mM	0.1560 mL	0.7798 mL	1.5596 mL	3.8991 mL
	30 mM	0.1300 mL	0.6498 mL	1.2997 mL	3.2492 mL
	40 mM	0.0975 mL	0.4874 mL	0.9748 mL	2.4369 mL
	50 mM	0.0780 mL	0.3899 mL	0.7798 mL	1.9495 mL
	60 mM	0.0650 mL	0.3249 mL	0.6498 mL	1.6246 mL
	80 mM	0.0487 mL	0.2437 mL	0.4874 mL	1.2185 mL
	100 mM	0.0390 mL	0.1950 mL	0.3899 mL	0.9748 mL

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Triclopyr55335-06-3Inhibitorinhibitorinhibit

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