Triclopyr
Based on 1 publication(s) in Google Scholar
Triclopyr, a foliar systemic herbicide and fungicide, is widely used for broadleaf and woody plant control. Triclopyr has severe toxicity.
For research use only. We do not sell to patients.
- Purity: 99.80%
- CAS No.: 55335-06-3
- Formula: C7H4Cl3NO3
- Molecular Weight:256.47
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Publications Citing Use of MedChemExpress (MCE) Triclopyr
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Biological Activity
Triclopyr (3 mM; 48 hours) treatment exhibits cytotoxicity against N2a cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Mouse neuroblastoma (N2a) cells
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Concentration:3 mM
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Incubation Time:48 hours
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Result:Decreased significantly for cell viability (P < 0.0001) compared to the untreated N2a cells.
Triclopyr exhibits moderate half-lives (dog 25 h and monkey 6.3 h) due to plasma clearance (18 mL/h/kg, 26 mL/h/kg respectively) following oral gavage (3 male beagle dogs ;0.5 mg/kg, 5 mg/kg and 20 mg/kg) and intravenous administration (1 male rhesus monkey; 30 mg/kg) [2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:3 male beagle dogs(7.2 - 7.9 kg), 1 male rhesus monkey [2]
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Dosage:0.5 mg/kg, 5 mg/kg, 20 mg/kg (beagle dog); 30 mg/kg (rhesus monkey)
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Administration:Oral gavage (beagle dog); intravenous (rhesus monkey)
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Result:T1/2s of 25 and 6.3 h for dogs and a monkey, respectively.
Chemical Information
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CAS No. 55335-06-3
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Appearance Solid
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Molecular Weight 256.47
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Formula C7H4Cl3NO3
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Color White to off-white
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SMILES
OC(COC1=NC(Cl)=C(Cl)C=C1Cl)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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Anal Chem
Exposome-Scale Investigation of Cl-/Br-Containing Chemicals Using High-Resolution Mass Spectrometry, Multistage Machine Learning, and Cloud Computing. [Abstract]2025 Jun 3;97(21):11099-11109. PMID: 40401576
Solvent & Solubility
DMSO : 125 mg/mL (487.39 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (276 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Tejaswini P Reddy, et al. Toxicity of neurons treated with herbicides and neuroprotection by mitochondria-targeted antioxidant SS31. Int J Environ Res Public Health. 2011 Jan;8(1):203-21. [Content Brief]
[2]. C Timchalk, et al. Pharmacokinetics of triclopyr (3,5,6-trichloro-2-pyridinyloxyacetic acid) in the beagle dog and rhesus monkey: perspective on the reduced capacity of dogs to excrete this organic acid relative to the rat, monkey, and human. Toxicol Appl Pharmacol. 1997 Jun;144(2):268-78. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.8991 mL | 19.4955 mL | 38.9909 mL | 97.4773 mL |
| 5 mM | 0.7798 mL | 3.8991 mL | 7.7982 mL | 19.4955 mL | |
| 10 mM | 0.3899 mL | 1.9495 mL | 3.8991 mL | 9.7477 mL | |
| 15 mM | 0.2599 mL | 1.2997 mL | 2.5994 mL | 6.4985 mL | |
| 20 mM | 0.1950 mL | 0.9748 mL | 1.9495 mL | 4.8739 mL | |
| 25 mM | 0.1560 mL | 0.7798 mL | 1.5596 mL | 3.8991 mL | |
| 30 mM | 0.1300 mL | 0.6498 mL | 1.2997 mL | 3.2492 mL | |
| 40 mM | 0.0975 mL | 0.4874 mL | 0.9748 mL | 2.4369 mL | |
| 50 mM | 0.0780 mL | 0.3899 mL | 0.7798 mL | 1.9495 mL | |
| 60 mM | 0.0650 mL | 0.3249 mL | 0.6498 mL | 1.6246 mL | |
| 80 mM | 0.0487 mL | 0.2437 mL | 0.4874 mL | 1.2185 mL | |
| 100 mM | 0.0390 mL | 0.1950 mL | 0.3899 mL | 0.9748 mL |
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