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Triclopyr 

Cat. No.: HY-B2051
Handling Instructions

Triclopyr, a foliar systemic herbicide and fungicide, is widely used for broadleaf and woody plant control. Triclopyr has severe toxicity.

For research use only. We do not sell to patients.

Triclopyr Chemical Structure

Triclopyr Chemical Structure

CAS No. : 55335-06-3

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Description

Triclopyr, a foliar systemic herbicide and fungicide, is widely used for broadleaf and woody plant control. Triclopyr has severe toxicity[1].

In Vitro

Triclopyr (3 mM; 48 hours) treatment exhibits cytotoxicity against N2a cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Cytotoxicity Assay[1]

Cell Line: Mouse neuroblastoma (N2a) cells
Concentration: 3 mM
Incubation Time: 48 hours
Result: Decreased significantly for cell viability (P < 0.0001) compared to the untreated N2a cells.
In Vivo

Pharmacokinetic Analysis
Triclopyr exhibits moderate half-lives (dog 25 h and monkey 6.3 h) due to plasma clearance (18 mL/h/kg, 26 mL/h/kg respectively) following oral gavage (3 male beagle dogs ;0.5 mg/kg, 5 mg/kg and 20 mg/kg) and intravenous administration (1 male rhesus monkey; 30 mg/kg) [2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 3 male beagle dogs(7.2 - 7.9 kg), 1 male rhesus monkey [2]
Dosage: 0.5 mg/kg, 5 mg/kg, 20 mg/kg (beagle dog); 30 mg/kg (rhesus monkey)
Administration: Oral gavage (beagle dog); intravenous (rhesus monkey)
Result: T1/2s of 25 and 6.3 h for dogs and a monkey, respectively.
Molecular Weight

256.47

Formula

C₇H₄Cl₃NO₃

CAS No.

55335-06-3

SMILES

OC(COC1=NC(Cl)=C(Cl)C=C1Cl)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

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Triclopyr
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HY-B2051
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