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Cat. No.: HY-178288

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TS-IN-7

TS-IN-7 (Compound 6) is a thymidylate synthase (TS) inhibitor with an IC₅₀ of 39 nM. TS-IN-7 can be used for the study of cancer chemotherapy.

For research use only. We do not sell to patients.

CAS No.: 150585-99-2
Formula: C₂₀H₂₁N₅O₆
Molecular Weight:427.41

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

TS-IN-7 Chemical Structure

CAS No.: 150585-99-2

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

TS-IN-7 (Compound 6) is a thymidylate synthase (TS) inhibitor with an IC₅₀ of 39 nM. TS-IN-7 can be used for the study of cancer chemotherapy^[1].

Chemical Information

CAS No. 150585-99-2
Molecular Weight 427.41
Formula C₂₀H₂₁N₅O₆
SMILES

CC(C1=CC=C(C=C1)C(N[C@H](C(O)=O)CCC(O)=O)=O)C2=CNC(NC(N)=N3)=C2C3=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Aso K, et al. Pyrrolo[2,3-d]pyrimidine thymidylate synthase inhibitors: design and synthesis of one-carbon bridge derivatives. Chem Pharm Bull (Tokyo). 2001 Oct;49(10):1280-7. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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