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Cat. No.: HY-119169

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Tubulozole

Tubulozole is an orally active synthetic microtubule inhibitor. Tubulozole can be used for the research of tumor.

For research use only. We do not sell to patients.

CAS No.: 84697-22-3
Formula: C₂₃H₂₃Cl₂N₃O₄S
Molecular Weight:508.42

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Tubulozole Chemical Structure

CAS No.: 84697-22-3

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vivo
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Tubulozole is an orally active synthetic microtubule inhibitor. Tubulozole can be used for the research of tumor^[1].

In Vivo

Tubulozole (oral; 160 mg/kg) has anti-microtubular and anti-tumor effect in vivo^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

Male CDFi (DBA/Px C3H) hybrids (18-22 g)^[1].
Dosage:

160 mg/kg
Administration:

Oral gavage
Result:

Had anti-microtubular and anti-tumor effect.

Chemical Information

CAS No. 84697-22-3
Molecular Weight 508.42
Formula C₂₃H₂₃Cl₂N₃O₄S
SMILES

O=C(NC1=CC=C(C=C1)SC[C@@H]2O[C@@](C3=CC=C(C=C3Cl)Cl)(OC2)CN4C=CN=C4)OCC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Distelmans W, et al. Influence of the synthetic microtubule inhibitor erbulozole (P.I.N.N.) (R 55 104), a new tubulozole congener, and gamma irradiation on murine tumors in vivo. Eur J Cancer Clin Oncol. 1989;25(10):1499-1504. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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