GEMSA
GEMSA is a potent inhibitor of enkephalin convertase (Ki=8.8 nM). GEMSA elicites analgesia.
For research use only. We do not sell to patients.
- Purity : 98%
- CAS No.: 77482-44-1
- Formula: C7H13N3O4S
- Molecular Weight:235.26
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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CPA inhibitorCPA Inhibitor -
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Carboxypeptidase G2 (CPG2) InhibitorCPG2 Inhibitor -
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GCPII-IN-1 TFAGCPII Inhibitor -
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2-Benzylsuccinic acid (Standard)CPA Inhibitor
Biological Activity
Description
IC50 & Target
Encephalin convertase, Ki 值为8.8 nM.
In Vitro
GEMSA inhibits the activation of TAFI and porcine CBB[1]. GEMSA can inhibit the prolongation of lysis time in recombinant BAP and does not lead to the lysis of APC fibronectin[1]. GEMSA inhibits the prolongation of lysis time in porcine CPB, TAFI, and recombinant BAP, APC with the EC50 values of 0.34 μM, 100μM, 115 μM, 90 μM respectively[1][2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 77482-44-1
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Appearance Solid
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Molecular Weight 235.26
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Formula C7H13N3O4S
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Color White to off-white
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SMILES
OC(C(SCCNC(N)=N)CC(O)=O)=O
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Synonyms
2-Guanidinoethylmercaptosuccinic acid
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (266 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
GEMSA Related Classifications
HY-118120 Related Classifications
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