2. Protein Tyrosine Kinase/RTK
  3. Syk
  4. Type-II-IN-1

Type-II-IN-1 (Compound 3) is a type II spleen tyrosine kinase (Syk) inhibitor with an IC50 of 2.1 nM. Type-II-IN-1 can bind to the DFG-out conformation of Syk. Type-II-IN-1 can be used for the research of immunology, such as asthma.

For research use only. We do not sell to patients.

Type-II-IN-1

Type-II-IN-1 Chemical Structure

CAS No. : 1419299-81-2

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Type-II-IN-1 Related Antibodies

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Description

Type-II-IN-1 (Compound 3) is a type II spleen tyrosine kinase (Syk) inhibitor with an IC50 of 2.1 nM. Type-II-IN-1 can bind to the DFG-out conformation of Syk. Type-II-IN-1 can be used for the research of immunology, such as asthma[1].

Molecular Weight

529.51

Formula

C29H22F3N5O2
CAS No.
SMILES

O=C(C1=CC=CC(C(F)(F)F)=C1)NC2=CC=C(C)C(C3=CC4=C(N(C)C3=O)N=C(NC5=CC=CC=C5)N=C4)=C2
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Type-II-IN-1 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Type-II-IN-11419299-81-2SykSpleen tyrosine kinaseInhibitorinhibitorinhibit

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HY-18911
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