Undec-10-ynoic acid
Based on 1 Customer Validation
Undec-10-ynoic acid (10-Undecynoic acid) is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity : 99.97%
- CAS No.: 2777-65-3
- Formula: C11H18O2
- Molecular Weight:182.26
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
All PROTAC Linkers Isoforms
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Biological Activity
Description
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E1119 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2777-65-3
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Appearance Solid
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Molecular Weight 182.26
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Formula C11H18O2
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Color White to light yellow
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SMILES
O=C(O)CCCCCCCCC#C
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Synonyms
10-Undecynoic acid
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (548.67 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
Purity & Documentation
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Data Sheet (238 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.4867 mL | 27.4333 mL | 54.8667 mL | 137.1667 mL |
| 5 mM | 1.0973 mL | 5.4867 mL | 10.9733 mL | 27.4333 mL | |
| 10 mM | 0.5487 mL | 2.7433 mL | 5.4867 mL | 13.7167 mL | |
| 15 mM | 0.3658 mL | 1.8289 mL | 3.6578 mL | 9.1444 mL | |
| 20 mM | 0.2743 mL | 1.3717 mL | 2.7433 mL | 6.8583 mL | |
| 25 mM | 0.2195 mL | 1.0973 mL | 2.1947 mL | 5.4867 mL | |
| 30 mM | 0.1829 mL | 0.9144 mL | 1.8289 mL | 4.5722 mL | |
| 40 mM | 0.1372 mL | 0.6858 mL | 1.3717 mL | 3.4292 mL | |
| 50 mM | 0.1097 mL | 0.5487 mL | 1.0973 mL | 2.7433 mL | |
| 60 mM | 0.0914 mL | 0.4572 mL | 0.9144 mL | 2.2861 mL | |
| 80 mM | 0.0686 mL | 0.3429 mL | 0.6858 mL | 1.7146 mL | |
| 100 mM | 0.0549 mL | 0.2743 mL | 0.5487 mL | 1.3717 mL |
Undec-10-ynoic acid Related Classifications
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