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Cat. No.: HY-187186

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Urease-IN-25

Urease-IN-25 (Compound 10a) is a urease inhibitor with an IC₅₀ value of 0.50 μM against jack bean urease. Urease-IN-25 can be used in the research of Helicobacter pylori infection, chronic gastritis, peptic ulcer disease, gastric cancer, mucosa-associated lymphoid tissue lymphoma, and other conditions.

For research use only. We do not sell to patients.

CAS No.: 115037-71-3
Formula: C₂₂H₁₉N₃O₄S
Molecular Weight:421.47

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Urease-IN-25 Chemical Structure

CAS No.: 115037-71-3

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Chemical Information

CAS No. 115037-71-3
Molecular Weight 421.47
Formula C₂₂H₁₉N₃O₄S
SMILES

O=C(N/C(C(NC1=CC=C(S(=O)(N)=O)C=C1)=O)=C\C2=CC=CC=C2)C3=CC=CC=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Mohammadi Oshnari A, et al. Diamide-based sulfonamide derivatives as new urease inhibitors: Synthesis, biological evaluation, and computational studies. Bioorganic chemistry. 2026 Sep 15;180:110240. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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