Anticancer agent 59
Anticancer agent 59 (compound 11) has inhibitory activity against kinds of cancer cell lines, especially in A549 with IC50 of 0.2 μM. Anticancer agent 59 induces apoptosis and an increase of Ca2+ and ROS in cancer cells. Anticancer agent 59 significantly decreases mitochondrial membrane potential. Anticancer agent 59 can suppress tumor growth in A549 mouse xenograft model.
For research use only. We do not sell to patients.
- CAS No.: 2366170-11-6
- Formula: C42H59NO6
- Molecular Weight:673.92
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
IC50: 0.2 μM in A549[1]
Chemical Information
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CAS No. 2366170-11-6
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Molecular Weight 673.92
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Formula C42H59NO6
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SMILES
C[C@]12[C@]3(C([C@@]4([H])[C@@](CC3)(CC[C@@](C)(C4)C(N[C@H](C(O)=O)CC5=CC=CC=C5)=O)C)=CC([C@]1([H])[C@@]6([C@@](C(C)([C@H](CC6)OC(CC)=O)C)([H])CC2)C)=O)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Anticancer agent 59 Related Classifications
HY-146462 Related Classifications
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