Copper(Ⅱ) sulfate
Based on 4 publication(s) in Google Scholar
Copper(Ⅱ) sulfate (Cupric sulfate) is an inorganic compound that is a source of copper ions. Copper(Ⅱ) sulfate forms coordination compounds through the coordination of copper ions with ligands. Copper(Ⅱ) sulfate can be used for various enzymatic studies and material synthesis.
For research use only. We do not sell to patients.
- Purity: 100.4%
- CAS No.: 7758-98-7
- Formula: CuSO4
- Molecular Weight:159.60
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Storage:
Store at room temperature, keep dry and cool.
In solvent -80°C, 1 year , -20°C, 6 months
Publications Citing Use of MedChemExpress (MCE) Copper(Ⅱ) sulfate
More-
Cell Proliferation/Viability Assay
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Cell Proliferation/Viability Assay
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WB
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Cell Imaging/Staining
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IF
Biological Activity
Copper(Ⅱ) sulfate can be used to synthesize anionic copper sulfate aggregates and chains for magnetic research[1].
Copper(Ⅱ) sulfate can be used in enzymatic reactions and material synthesis[1].
Copper(Ⅱ) sulfate can be used as a copper supplement in animal nutrition to evaluate bioavailability[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 7758-98-7
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Appearance Solid
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Molecular Weight 159.60
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Formula CuSO4
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Color White to off-white
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SMILES
O=S(=O)=[Cu](=O)=O
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Synonyms
Cupric sulfate
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature, keep dry and cool
In solvent -80°C 1 year -20°C 6 months
Publications (4)
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Journal Impact Factor
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Most Recent
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Adv Sci (Weinh)
TRIM21-Mediated K11-Linked Ubiquitination of ID1 Suppresses Tumorigenesis and Promotes Cuproptosis in Esophageal Squamous Cell Carcinoma. [Abstract]2025 Jul 13:e02501. PMID: 40652518
Copper(Ⅱ) sulfate purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Jul 13:e02501. [Abstract]
Cell viability assays in TRIM21-knockdown KYSE30 and KYSE450 cells treated with Copper(Ⅱ) sulfate (CuSO4) (0.5 mM; 24-48 h).
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Pharmacol Res
Sirtuin3 attenuates pressure overload-induced pathological myocardial remodeling by inhibiting cardiomyocyte cuproptosis. [Abstract]2025 Jun:216:107739. PMID: 40250507
Copper(Ⅱ) sulfate purchased from MedChemExpress. Usage Cited in: Pharmacol Res. 2025 Jun:216:107739. [Abstract]
Copper(Ⅱ) sulfate (0.01-1 μM; 24 h) significantly decreased cell viability of cardiomyocytes.
Copper(Ⅱ) sulfate purchased from MedChemExpress. Usage Cited in: Pharmacol Res. 2025 Jun:216:107739. [Abstract]
Copper(II) sulfate (0.01-1 μM; 24 h) significantly decreased the SIRT3 protein content in NRVMs.
Copper(Ⅱ) sulfate purchased from MedChemExpress. Usage Cited in: Pharmacol Res. 2025 Jun:216:107739. [Abstract]
Copper(II) sulfate (200 nM; 24 h). Representative images of cellular morphology and quantifications MFI of copper ion fluorescence in NRVMs.
Copper(Ⅱ) sulfate purchased from MedChemExpress. Usage Cited in: Pharmacol Res. 2025 Jun:216:107739. [Abstract]
Copper(II) sulfate (200 nM; 24 h). Representative immunofluorescent staining and quantifications of DLAT, mitotracker, and SIRT3 expression in NRVMs.
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Environ Int
Low dosage exposure of deoxynivalenol and copper synergistically enhanced the intestinal toxicity. [Abstract]2025 Oct 28:205:109891. PMID: 41172574 -
Cell Rep
4-octyl itaconate inhibits cytokine-mediated inflammation via alkylation of TYK2 and JAK1. [Abstract]2026 Mar 30;45(4):117179. PMID: 41915469
Solvent & Solubility
H2O : 100 mg/mL (626.57 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (276 KB)
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SDS (759 KB)
- English - EN (759 KB)
- Français - FR (759 KB)
- Deutsch - DE (759 KB)
- Norwegian - NO (759 KB)
- Español - ES (759 KB)
- Swedish - SV (759 KB)
- Italian - IT (759 KB)
- Korean - KR (759 KB)
- Portuguese - PT (759 KB)
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Handling Instructions (2659 KB)
References
[1]. Burrows AD, et al. Synthesis, structures, and magnetic behavior of new anionic copper(II) sulfate aggregates and chains. Inorg Chem. 2012 Oct 15;51(20):10983-9. [Content Brief]
[2]. Du Z, et al. Utilization of copper in copper proteinate, copper lysine, and cupric sulfate using the rat as an experimental model. J Anim Sci. 1996 Jul;74(7):1657-63. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 6.2657 mL | 31.3283 mL | 62.6566 mL | 156.6416 mL |
| 5 mM | 1.2531 mL | 6.2657 mL | 12.5313 mL | 31.3283 mL | |
| 10 mM | 0.6266 mL | 3.1328 mL | 6.2657 mL | 15.6642 mL | |
| 15 mM | 0.4177 mL | 2.0886 mL | 4.1771 mL | 10.4428 mL | |
| 20 mM | 0.3133 mL | 1.5664 mL | 3.1328 mL | 7.8321 mL | |
| 25 mM | 0.2506 mL | 1.2531 mL | 2.5063 mL | 6.2657 mL | |
| 30 mM | 0.2089 mL | 1.0443 mL | 2.0886 mL | 5.2214 mL | |
| 40 mM | 0.1566 mL | 0.7832 mL | 1.5664 mL | 3.9160 mL | |
| 50 mM | 0.1253 mL | 0.6266 mL | 1.2531 mL | 3.1328 mL | |
| 60 mM | 0.1044 mL | 0.5221 mL | 1.0443 mL | 2.6107 mL | |
| 80 mM | 0.0783 mL | 0.3916 mL | 0.7832 mL | 1.9580 mL | |
| 100 mM | 0.0627 mL | 0.3133 mL | 0.6266 mL | 1.5664 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.