S 33138
S33138 is a D3 receptor antagonist. S33138 inhibits addiction in animal models of addiction. S33138 reduces cognitive impairment in rodent and primate models of schizophrenia and Parkinson's disease. S33138 can be used in research on neurological disorders such as schizophrenia and Parkinson's disease.
For research use only. We do not sell to patients.
- CAS No.: 245514-32-3
- Formula: C22H23N3O2
- Molecular Weight:361.44
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Dopamine Receptor Isoforms
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Biological Activity
Chemical Information
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CAS No. 245514-32-3
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Molecular Weight 361.44
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Formula C22H23N3O2
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SMILES
CC(NC(C=C1)=CC=C1CCN2C[C@@H]3[C@@H](C2)COC4=CC=C(C#N)C=C43)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Peng XQ, et al.. The preferential dopamine D3 receptor antagonist S33138 inhibits cocaine reward and cocaine-triggered relapse to drug-seeking behavior in rats. Neuropharmacology. 2009 Mar;56(4):752-60. [Content Brief]
[2]. Millan MJ, et al. The dopamine D3 receptor antagonist, S33138, counters cognitive impairment in a range of rodent and primate procedures. Int J Neuropsychopharmacol. 2010 Sep;13(8):1035-51. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)