1. Protein Tyrosine Kinase/RTK
    Apoptosis
  2. VEGFR
    Apoptosis
  3. VEGFR-2-IN-13

VEGFR-2-IN-13 

Cat. No.: HY-144754
Handling Instructions

VEGFR-2-IN-13 (Compound 19a) is a potent VEGFR-2 inhibitor with an IC50 of 3.4 nM. VEGFR-2-IN-13 disrupts the HepG2 cell cycle by arresting the G2/M phase and induces apoptosis.

For research use only. We do not sell to patients.

VEGFR-2-IN-13 Chemical Structure

VEGFR-2-IN-13 Chemical Structure

Size Stock
100 mg   Get quote  
250 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

VEGFR-2-IN-13 (Compound 19a) is a potent VEGFR-2 inhibitor with an IC50 of 3.4 nM. VEGFR-2-IN-13 disrupts the HepG2 cell cycle by arresting the G2/M phase and induces apoptosis[1].

IC50 & Target

VEGFR2

3.4 nM (IC50)

In Vitro

VEGFR-2-IN-13 (Compound 19a) shows anti-proliferative activities with IC50 values of 8.2 µM and 5.4 µM against MCF-7 and HepG2 cells, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

454.50

Formula

C24H18N6O2S

SMILES

O=C(NC1=CC=C(C=C1)C(NC2=CC=CC=C2)=O)CSC3=NC4=C(N5C=NN=C35)C=CC=C4

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email address *

Phone number *

 

Organization name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
VEGFR-2-IN-13
Cat. No.:
HY-144754
Quantity:
MCE Japan Authorized Agent: