Venuloside A
Based on 1 Customer Validation
Venuloside A is a potent inhibitor of LAT3. Venuloside A inhibits the leucine uptake in LNCaP prostate cancer cells with an IC50 of 8.12 μM.
For research use only. We do not sell to patients.
- Purity : 99.82%
- CAS No.: 1609278-97-8
- Formula: C23H36O7
- Molecular Weight:424.53
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| LNCaP | IC50 |
8.12 μM
Compound: 1, ESK246
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Inhibition of LAT in human LNCAP cells assessed as inhibition of [3H]-L-leucine transport by liquid scintillation counting analysis
Inhibition of LAT in human LNCAP cells assessed as inhibition of [3H]-L-leucine transport by liquid scintillation counting analysis
|
[PMID: 25984885] |
Chemical Information
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CAS No. 1609278-97-8
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Appearance Solid
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Molecular Weight 424.53
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Formula C23H36O7
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Color White to off-white
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SMILES
CC(C)([C@@H]1CCC(C)=CC1)O[C@H]2[C@@H]([C@H]([C@H]([C@H](O2)C)O)OC(/C=C(C)/C)=O)OC(C)=O
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Synonyms
ESK246
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
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Data Sheet (266 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)