1. Saccharides and Glycosides
  2. Verbascose

Verbascose 

Cat. No.: HY-N9369
Handling Instructions

Verbascose, an alacto-oligosac-charides (GOS), has potent immunostimulatory activity. Verbascose acts as a potential natural immunomodulatory agent.

For research use only. We do not sell to patients.

Verbascose Chemical Structure

Verbascose Chemical Structure

CAS No. : 546-62-3

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Description

Verbascose, an alacto-oligosac-charides (GOS), has potent immunostimulatory activity. Verbascose acts as a potential natural immunomodulatory agent[1].

In Vitro

Verbascose (25, 50, 100, 200, 400 μg/mL; 12, 24, 36, 48 hours) significantly increases the viability of RAW264.7 cells[1].
Verbascose has notable activity of promoting peritoneal macrophages to devour neutral red in a dose-dependent manner and exhibits its maximum activity of cell phagocytosis at a concentration of 200 μg/mL[1].
Verbascose induces significant increases of NO production. Verbascose can enhance the ability of devouring neutral red of peritoneal macrophages and promote the release of nitric oxide and immune reactive molecules such as interleukin (IL)-6, IL-1β, interferon (IFN)-α, and IFN-γ[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Verbascose (30, 90, 120 mg/kg/day; sc; for 8 days) at a medium dose of 90 mg/kg body weight can significantly increase the index of spleen, activity of lysozyme in spleen and serum, hemolysin level in serum, and swelling rate of earlap in the delayed type of hypersensitivity (DTH) of immunosuppressed female Kunming mice[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

828.72

Formula

C₃₀H₅₂O₂₆

CAS No.
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Verbascose
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