Dexamethasone impurity 2-d5
Betamethasone 21-phosphate-d5 is the deuterium labeled Betamethasone disodium phosphate. Betamethasone disodium phosphate (Betamethasone 21-phosphate disodium salt) is a kind of corticosteroid, which is commonly used in the intralesional research of keloids.
For research use only. We do not sell to patients.
- Formula: C22H25D5FO8P
- Molecular Weight:477.47
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 360-63-4
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Molecular Weight 477.47
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Formula C22H25D5FO8P
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SMILES
C[C@@]12[C@](C[C@@H]([C@]2(O)C(C([2H])([2H])OP(O)(O)=O)=O)C)([H])[C@@]3([H])[C@@]([C@@]4(C(C([2H])([2H])C3)=C([2H])C(C=C4)=O)C)([C@H](C1)O)F
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Synonyms
Betamethasone phosphate-d5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Wang L, et al. Determination of betamethasone disodium phosphate in the in vitro media of PLGA microspheres by high-performance liquid chromatography. J Pharm Biomed Anal. 2002;28(3-4):629-635. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)