VUF11211
VUF11211 is an allosteric inverse CXCR3 agonist with a Kd of 0.65 nM.
For research use only. We do not sell to patients.
- CAS No.: 906556-51-2
- Formula: C26H35Cl2N5O
- Molecular Weight:504.50
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Kd: 0.65 nM (CXCR3)[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| BaF3 | IC50 |
0.3 nM
Compound: 1
|
Displacement of [125I]CXCL10 from human CXCR3 expressed in mouse BA/F3 cells
Displacement of [125I]CXCL10 from human CXCR3 expressed in mouse BA/F3 cells
|
[PMID: 22018463] |
Chemical Information
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CAS No. 906556-51-2
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Molecular Weight 504.50
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Formula C26H35Cl2N5O
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SMILES
ClC1=CC=C(C=C1)CN2CCC(CC2)N3[C@H](CN(CC3)C4=NC=C(C=C4Cl)C(NCC)=O)CC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)