Woodtide
Woodtide is a substrate for the DYRK (DYRK) family of kinases whose sequence is based on that around the DYRK phosphorylation site in FKHR.
For research use only. We do not sell to patients.
- CAS No.: 634592-23-7
- Formula: C68H122N20O21S
- Molecular Weight:1587.88
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Immunoprecipitated FLAG-dDYRK2 or FLAG-MNB is assayed using 50 μM Woodtide or 50 μM activation-loop peptide with two additional lysines attached to the N terminus to allow it to bind to P81 paper (KKSSCYVDRKIYTYIQSRFY for dDYRK2 or KKSSCQLGQRIYHYIQSRFY for MNB). Both kinases efficiently phosphorylated the synthetic exogenous substrate peptide Woodtide, but neither dDYRK2 nor MNB phosphorylated their activation-loop peptide[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 634592-23-7
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Molecular Weight 1587.88
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Formula C68H122N20O21S
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Sequence Shortening
KKISGRLSPIMTEQ
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Pamela A Lochhead, et al. Activation-loop autophosphorylation is mediated by a novel transitional intermediate form of DYRKs. Cell. 2005 Jun 17;121(6):925-36. [Content Brief]
[2]. Linda E Campbell, et al. Differing substrate specificities of members of the DYRK family of arginine-directed protein kinases. FEBS Lett. 2002 Jan 2;510(1-2):31-6. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Woodtide Related Classifications
HY-P3812 Related Classifications
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