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Cat. No.: HY-182431

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Wy 45086

Wy 45086 is a histamine H₂ receptor antagonist. Wy 45086 blocks the H₂ receptor signaling pathway and inhibits gastric acid secretion in experimental animals. Wy 45086 can be used in ulcer-related research.

For research use only. We do not sell to patients.

CAS No.: 87476-50-4
Formula: C₂₂H₂₇N₃O₃S
Molecular Weight:413.53

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Wy 45086 Chemical Structure

CAS No.: 87476-50-4

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vivo
Chemical Information
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Biological Activity

Description

All Histamine Receptor Isoforms :

In Vivo

Wy 45086 exerts significant inhibitory effects on gastric acid secretion in pylorus-ligated rats and dogs with innervated gastric pouches, with a ED₅₀ of 1 mg/kg in both species^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 87476-50-4
Molecular Weight 413.53
Formula C₂₂H₂₇N₃O₃S
SMILES

O=S1(N=C(C2=C1C=CC=C2)NCCCOC3=CC=CC(CN4CCCCC4)=C3)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Nielsen ST. Inhibition of gastric acid secretion by H2-receptor antagonists. Arch Int Pharmacodyn Ther. 1986 Jul;282(1):151-60.
[Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- In Vivo
Chemical Information
Purity & Documentation
References

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Wy 45086

All Histamine Receptor Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Wy 45086 Related Classifications

HY-182431 Related Classifications