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Cat. No.: HY-N12304

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Xanthalin

Name: Xanthalin
Brand: MedChemExpress
SKU: HY-N12304
Price: 316.00 USD
Availability: InStock
Rating: 5 (2 reviews)

2 Cited Publications

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Based on 2 publication(s) in Google Scholar

Xanthalin is a naturally occurring, orally active linear dihydropyranocoumarin. Xanthalin acts as an inhibitor of Spodoptera littoralis neonate larval growth and reduces larval body weight. Xanthalin is used in research related to pest control.

For research use only. We do not sell to patients.

Purity : 99.28%
CAS No.: 21800-48-6
Formula: C₂₄H₂₆O₇
Molecular Weight:426.46

Storage:

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Xanthalin Chemical Structure

CAS No.: 21800-48-6

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
- In Vivo
Chemical Information
Publications (2)
Purity & Documentation
References
Calculators
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Bioz

Biological Activity

Description

In Vitro

Xanthalin (1 g; 2 min) undergoes methanolic potassium hydroxide saponification to yield 3'-angeloyl-4'-methoxy-3',4'-dihydroxanthyletin^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Xanthalin (compound 20) (1-5 μmol/g fresh weight diet; fed for 6 days) inhibits the growth of neonate larvae of Spodoptera littoralis^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

Spodoptera littoralis (neonate larvae, laboratory colony)^[1]
Dosage:

1, 2, 3, 4, 5 μmol/g fresh wt
Administration:

fed for 6 days
Result:

Reduced larval growth to 0%, 3%, 17%, 3%, and 34% of control at 1.0, 2.0, 3.0, 4.0, and 5.0 μmol/g fresh wt, respectively.
Corresponded to growth inhibition values of 100%, 97%, 83%, 97%, and 66%.

Chemical Information

CAS No. 21800-48-6
Appearance Solid
Molecular Weight 426.46
Formula C₂₄H₂₆O₇
Color White to off-white
SMILES

C/C=C(C)\C(O[C@@H]1C2=CC(C=CC(O3)=O)=C3C=C2OC(C)([C@@H]1OC(/C(C)=C\C)=O)C)=O
Structure Classification
- Phenylpropanoids
- Coumarins
Initial Source
- Plants
- Umbelliferae
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Publications (2)

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Journal Impact Factor

J Cardiovasc Transl Res

Xanthatin Attenuates Angiotensin II-Induced Cardiac Hypertrophy by Targeting CREB5. [Abstract]

2026 May 19;19(1):55. PMID: 42156597
Biomed Pharmacother

Targeted inhibition of STAT3 (Tyr705) by xanthatin alleviates osteoarthritis progression through the NF-κB signaling pathway. [Abstract]

2024 May:174:116451. PMID: 38520869

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (296 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Hadaček F, et al. Analysis, isolation and insecticidal activity of linear furanocoumarins and other coumarin derivatives fromPeucedanum (Apiaceae: Apioideae). Journal of chemical ecology. 1994 Aug;20(8):2035-54. [Content Brief]

[2]. Zheleva A, et al. Natural Coumarins V: Isolation of Xanthalin and a New Pyranocoumarin, Peuarenine, from Peucedanum arenarium W.K. Journal of Pharmaceutical Sciences, 1972, 61(10): 1643-1644.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
- In Vitro
- In Vivo
Chemical Information
Publications (2)
Purity & Documentation
References

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Xanthalin

Publications Citing Use of MedChemExpress (MCE) Xanthalin