1. Metabolic Enzyme/Protease
  2. Drug Metabolite
  3. (Z)-10-Hydroxynortriptyline-d3

(Z)-10-Hydroxynortriptyline-d3 

Cat. No.: HY-100646AS Purity: ≥99.0%
COA Handling Instructions

(Z)-10-Hydroxynortriptyline-d3 is the deuterium labeled (Z)-10-Hydroxynortriptyline (HY-100646A). (Z)-10-Hydroxynortriptyline is a metabolite of Nortriptyline (HY-118620). Nortriptyline is a tricyclic antidepressant and the main active metabolite of Amitriptyline, and is used to relieve the symptoms of depression[1][2].

For research use only. We do not sell to patients.

(Z)-10-Hydroxynortriptyline-d<sub>3</sub> Chemical Structure

(Z)-10-Hydroxynortriptyline-d3 Chemical Structure

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Based on 1 publication(s) in Google Scholar

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Description

(Z)-10-Hydroxynortriptyline-d3 is the deuterium labeled (Z)-10-Hydroxynortriptyline (HY-100646A). (Z)-10-Hydroxynortriptyline is a metabolite of Nortriptyline (HY-118620). Nortriptyline is a tricyclic antidepressant and the main active metabolite of Amitriptyline, and is used to relieve the symptoms of depression[1][2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

282.40

Formula

C19H18D3NO

Appearance

Solid

Color

White to light yellow

SMILES

OC1C2=CC=CC=C2/C(C3=CC=CC=C3C1)=C\CCNC([2H])([2H])[2H]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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(Z)-10-Hydroxynortriptyline-d3 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
(Z)-10-Hydroxynortriptyline-d3
Cat. No.:
HY-100646AS
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