ZINC08438472
ZINC08438472 is a potent and selective peroxisome proliferator activated receptors-α (PPAR-α) agonist with an EC50 value of 12.1 nM. ZINC08438472 is promising for research of diabetes, hyperlipidaemia and inflammatory disorders.
For research use only. We do not sell to patients.
- CAS No.: 443872-20-6
- Formula: C25H25NO8S
- Molecular Weight:499.53
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK-293T | EC50 |
12.1 nM
Compound: ZINC08438472
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Agonist activity at GAL4-tagged PPARalpha ligand-binding domain (unknown origin) expressed in HEK293T cells incubated for 16 to 19 hrs by beta-lactamase reporter gene assay
Agonist activity at GAL4-tagged PPARalpha ligand-binding domain (unknown origin) expressed in HEK293T cells incubated for 16 to 19 hrs by beta-lactamase reporter gene assay
|
[PMID: 25491112] |
Chemical Information
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CAS No. 443872-20-6
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Molecular Weight 499.53
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Formula C25H25NO8S
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SMILES
O=C(C(C/1=O)=C(NC2=CC=C(OCC)C=C2)SC1=C\C3=CC=C(OCC(O)=O)C(OC)=C3)OCC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)