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Cat. No.: HY-157796

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β2AR agonist 4

β2AR agonist 4 (compound A19) is a potent and selective β2-Adrenoceptor agonist with an EC₅₀ of 3.7 pM. β2AR agonist 4 suppresses the inflammatory cytokines and leukocytes upregulation and improves lung function in COPD rat model.

For research use only. We do not sell to patients.

Formula: C₁₉H₂₃ClN₂O₅
Molecular Weight:394.85

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

β2AR agonist 4 Chemical Structure

Size

Price

Stock

Quantity

Sample (0.1mg)

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(In Japan)

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

All Adrenergic Receptor Isoforms :

Chemical Information

Molecular Weight 394.85
Formula C₁₉H₂₃ClN₂O₅
SMILES

OC1=CC=C(C(OC2)=C1NC2=O)C(CNCCC3=CC=CC=C3OC)O.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Xing G, et al. Discovery and Identification of Novel 5-Hydroxy-4 H-benzo [1, 4] oxazin-3-one Derivatives as Potent β2-Adrenoceptor Agonists through Structure-Based Design, Synthesis, and Biological Evaluation[J]. Journal of Medicinal Chemistry, 2024.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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