δ-Decalactone
Based on 1 Customer Validation
δ-Decalactone is a hydrophobic natural cyclic lactone aroma compound with a creamy-coconut-peach aroma. It serves as a flavoring agent and a renewable monomer for ring-opening polymerization to prepare homopolymers and amphiphilic block copolymers, and it can self-assemble into degradable micelles for the encapsulation of hydrophobic molecules. δ-Decalactone is used in food flavoring and polymer materials research.
For research use only. We do not sell to patients.
- Purity : 99.63%
- CAS No.: 705-86-2
- Formula: C10H18O2
- Molecular Weight:170.25
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
δ-Decalactone undergoes TBD-catalyzed ROP with PEG under solvent-free and mild conditions to form amphiphilic diblock and triblock copolymers, which exhibit semicrystalline properties originating from the PEG blocks and amorphous PDL segments[1].
δ-Decalactone (200 ppm; 48 h) shows a strong preference for the paraffin oil phase relative to the aqueous phase (P∞ ≈ 9.8-10.0 in the absence of emulsifier); the addition of 1% sucrose stearate-palmitate emulsifier reduces the oil/water partition coefficient to 2.88-3.77, with no significant pH dependence at pH 4.5 and 5.2[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 705-86-2
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Appearance Liquid (Density: 0.954 g/cm3)
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Molecular Weight 170.25
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Formula C10H18O2
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Color Colorless to light yellow
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SMILES
O=C1CCCC(CCCCC)O1
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (587.37 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo:
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (14.68 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (14.68 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (276 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 5.8737 mL | 29.3686 mL | 58.7372 mL | 146.8429 mL |
| 5 mM | 1.1747 mL | 5.8737 mL | 11.7474 mL | 29.3686 mL | |
| 10 mM | 0.5874 mL | 2.9369 mL | 5.8737 mL | 14.6843 mL | |
| 15 mM | 0.3916 mL | 1.9579 mL | 3.9158 mL | 9.7895 mL | |
| 20 mM | 0.2937 mL | 1.4684 mL | 2.9369 mL | 7.3421 mL | |
| 25 mM | 0.2349 mL | 1.1747 mL | 2.3495 mL | 5.8737 mL | |
| 30 mM | 0.1958 mL | 0.9790 mL | 1.9579 mL | 4.8948 mL | |
| 40 mM | 0.1468 mL | 0.7342 mL | 1.4684 mL | 3.6711 mL | |
| 50 mM | 0.1175 mL | 0.5874 mL | 1.1747 mL | 2.9369 mL | |
| 60 mM | 0.0979 mL | 0.4895 mL | 0.9790 mL | 2.4474 mL | |
| 80 mM | 0.0734 mL | 0.3671 mL | 0.7342 mL | 1.8355 mL | |
| 100 mM | 0.0587 mL | 0.2937 mL | 0.5874 mL | 1.4684 mL |
δ-Decalactone Related Classifications
HY-W016979 Related Classifications
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