2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. nAChR
  4. κ-Bungarotoxin

κ-Bungarotoxin (κ-Bgt) is a potent, selective, and slowly reversible antagonist of α3β2 neuronal nicotinic acetylcholine receptors with an IC50 of 2.30 nM.

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κ-Bungarotoxin Chemical Structure

κ-Bungarotoxin Chemical Structure

CAS No. : 124511-67-7

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κ-Bungarotoxin Related Antibodies

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Description

κ-Bungarotoxin (κ-Bgt) is a potent, selective, and slowly reversible antagonist of α3β2 neuronal nicotinic acetylcholine receptors with an IC50 of 2.30 nM[1].

IC50 & Target

IC50: 2.30 nM (recombinantly expressed in P. pastoris against α3β2)[1]
Molecular Weight

7265.22

Formula

C303H475N91O97S10
CAS No.
Sequence

Arg-Thr-Cys-Leu-Ile-Ser-Pro-Ser-Ser-Thr-Pro-Gln-Thr-Cys-Pro-Asn-Gly-Gln-Asp-Ile-Cys-Phe-Leu-Lys-Ala-Gln-Cys-Asp-Lys-Phe-Cys-Ser-Ile-Arg-Gly-Pro-Val-Ile-Glu-Gln-Gly-Cys-Val-Ala-Thr-Cys-Pro-Gln-Phe-Arg-Ser-Asn-Tyr-Arg-Ser-Leu-Leu-Cys-Cys-Thr-Thr-Asp-Asn-Cys-Asn-His (Disulfide bridge:Cys3-Cys21, Cys14-Cys42, Cys27-Cys31, Cys46-Cys58, Cys59-Cys64)
Sequence Shortening

RTCLISPSSTPQTCPNGQDICFLKAQCDKFCSIRGPVIEQGCVATCPQFRSNYRSLLCCTTDNCNH (Disulfide bridge:Cys3-Cys21, Cys14-Cys42, Cys27-Cys31, Cys46-Cys58, Cys59-Cys64)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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κ-Bungarotoxin Related Classifications

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

κ-Bungarotoxin124511-67-7κ-BgtnAChRNicotinic acetylcholine receptorsBungarus multicinctussnake venomneurotoxinInhibitorinhibitorinhibit

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