1,3-Propanedithiol
Based on 1 Customer Validation
1,3-Propanedithiol is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity : 99.16%
- CAS No.: 109-80-8
- Formula: C3H8S2
- Molecular Weight:108.22
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Storage:
RT, sealed storage, away from moisture and light.
In solvent -80°C, 1 year , -20°C, 6 months
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
All PROTAC Linkers Isoforms
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Biological Activity
Description
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E73 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 109-80-8
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Appearance Liquid (Density: 1.078 g/cm³)
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Molecular Weight 108.22
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Formula C3H8S2
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Color Colorless to off-white
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SMILES
SCCCS
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
RT, sealed storage, away from moisture and light
In solvent -80°C 1 year -20°C 6 months
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (924.04 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
Purity & Documentation
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Data Sheet (240 KB)
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SDS (631 KB)
- English - EN (631 KB)
- Français - FR (631 KB)
- Deutsch - DE (631 KB)
- Norwegian - NO (631 KB)
- Español - ES (631 KB)
- Swedish - SV (631 KB)
- Italian - IT (631 KB)
- Korean - KR (631 KB)
- Portuguese - PT (631 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 9.2404 mL | 46.2022 mL | 92.4044 mL | 231.0109 mL |
| 5 mM | 1.8481 mL | 9.2404 mL | 18.4809 mL | 46.2022 mL | |
| 10 mM | 0.9240 mL | 4.6202 mL | 9.2404 mL | 23.1011 mL | |
| 15 mM | 0.6160 mL | 3.0801 mL | 6.1603 mL | 15.4007 mL | |
| 20 mM | 0.4620 mL | 2.3101 mL | 4.6202 mL | 11.5505 mL | |
| 25 mM | 0.3696 mL | 1.8481 mL | 3.6962 mL | 9.2404 mL | |
| 30 mM | 0.3080 mL | 1.5401 mL | 3.0801 mL | 7.7004 mL | |
| 40 mM | 0.2310 mL | 1.1551 mL | 2.3101 mL | 5.7753 mL | |
| 50 mM | 0.1848 mL | 0.9240 mL | 1.8481 mL | 4.6202 mL | |
| 60 mM | 0.1540 mL | 0.7700 mL | 1.5401 mL | 3.8502 mL | |
| 80 mM | 0.1155 mL | 0.5775 mL | 1.1551 mL | 2.8876 mL | |
| 100 mM | 0.0924 mL | 0.4620 mL | 0.9240 mL | 2.3101 mL |
1,3-Propanedithiol Related Classifications
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