1,7-Heptanediol
Based on 1 Customer Validation
1,7-Heptanediol is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity : 99.53%
- CAS No.: 629-30-1
- Formula: C7H16O2
- Molecular Weight:132.20
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
All PROTAC Linkers Isoforms
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Biological Activity
Description
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E90 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 629-30-1
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Appearance <17°C Solid,>19°C Liquid
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Molecular Weight 132.20
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Formula C7H16O2
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SMILES
OCCCCCCCO
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (756.43 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (239 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 7.5643 mL | 37.8215 mL | 75.6430 mL | 189.1074 mL |
| 5 mM | 1.5129 mL | 7.5643 mL | 15.1286 mL | 37.8215 mL | |
| 10 mM | 0.7564 mL | 3.7821 mL | 7.5643 mL | 18.9107 mL | |
| 15 mM | 0.5043 mL | 2.5214 mL | 5.0429 mL | 12.6072 mL | |
| 20 mM | 0.3782 mL | 1.8911 mL | 3.7821 mL | 9.4554 mL | |
| 25 mM | 0.3026 mL | 1.5129 mL | 3.0257 mL | 7.5643 mL | |
| 30 mM | 0.2521 mL | 1.2607 mL | 2.5214 mL | 6.3036 mL | |
| 40 mM | 0.1891 mL | 0.9455 mL | 1.8911 mL | 4.7277 mL | |
| 50 mM | 0.1513 mL | 0.7564 mL | 1.5129 mL | 3.7821 mL | |
| 60 mM | 0.1261 mL | 0.6304 mL | 1.2607 mL | 3.1518 mL | |
| 80 mM | 0.0946 mL | 0.4728 mL | 0.9455 mL | 2.3638 mL | |
| 100 mM | 0.0756 mL | 0.3782 mL | 0.7564 mL | 1.8911 mL |