2. Natural Products
  3. Plants Alkaloids
  4. Stemonaceae Other Alkaloids
  5. Stemona tuberosa Lour.
  6. 10-Hydroxycroomine

10-Hydroxycroomine is a croomine-type alkaloid. 10-Hydroxycroomine can be isolated from the roots of Stemona tuberosa. 10-Hydroxycroomine produces a non-statistically significant reduction in Citric acid (HY-N1428)-induced coughing. 10-Hydroxycroomine can be used for the research of cough.

For research use only. We do not sell to patients.

10-Hydroxycroomine

10-Hydroxycroomine Chemical Structure

CAS No. : 1068009-94-8

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10-Hydroxycroomine Related Antibodies

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Description

10-Hydroxycroomine is a croomine-type alkaloid. 10-Hydroxycroomine can be isolated from the roots of Stemona tuberosa. 10-Hydroxycroomine produces a non-statistically significant reduction in Citric acid (HY-N1428)-induced coughing. 10-Hydroxycroomine can be used for the research of cough[1].

In Vivo

10-Hydroxycroomine (0.25 μmol; icv) produces a non-statistically significant 15-33% reduction in citric acid-induced coughing in Dunkin-Hartley guinea pigs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Dunkin-Hartley[1]
Dosage: 0.25 μmol
Administration: intracerebroventricular; single dose
Result: Decreased citric acid-induced coughing by 15-33%, but this inhibition was not statistically significant (P > 0.05).
Molecular Weight

337.41

Formula

C18H27NO5
CAS No.
SMILES

O[C@@H]1[C@]2(OC([C@@H]1C)=O)[C@@]3([H])N(CCCC2)[C@@]([C@]4([H])C[C@@H](C(O4)=O)C)([H])CC3
Structure Classification
Initial Source
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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10-Hydroxycroomine Related Classifications

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Keywords:

10-Hydroxycroomine1068009-94-8OthersStemona alkaloidDunkin-Hartley guinea pigsStemona tuberosaantitussive agentguinea pigscitric acid-induced coughingintracerebroventricular administrationInhibitorinhibitorinhibit

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