15-Hydroxydehydroabietic acid
15-Hydroxydehydroabietic acid is a diterpene compound isolated from the leaves of armand pine.
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- CAS. Nr.: 54113-95-0
- Formel: C20H28O3
- Molecular Weight:316.43
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
>10 μM
Compound: 20
|
Cytotoxicity in human A549 cells by SRB assay
Cytotoxicity in human A549 cells by SRB assay
|
[PMID: 26812172] |
| HCT-116 | IC50 |
>10 μM
Compound: 20
|
Cytotoxicity in human HCT116 cells by SRB assay
Cytotoxicity in human HCT116 cells by SRB assay
|
[PMID: 26812172] |
| HEK293 | IC50 |
>100 μg/mL
Compound: 32
|
Inhibition of TNF-alpha-induced NF-kappaB activity in human pNF-kappaB-luc-293 cells
Inhibition of TNF-alpha-induced NF-kappaB activity in human pNF-kappaB-luc-293 cells
|
[PMID: 20022253] |
| LoVo | IC50 |
>25 μg/mL
Compound: 32
|
Antiproliferative activity against human LoVo cells
Antiproliferative activity against human LoVo cells
|
[PMID: 20022253] |
| QGY-7703 | IC50 |
>25 μg/mL
Compound: 32
|
Antiproliferative activity against human QGY7703 cells
Antiproliferative activity against human QGY7703 cells
|
[PMID: 20022253] |
| RAW264.7 | IC50 |
76.4 μg/mL
Compound: 32
|
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO release
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO release
|
[PMID: 20022253] |
| SK-MEL-2 | IC50 |
>10 μM
Compound: 20
|
Cytotoxicity in human SK-MEL-2 cells by SRB assay
Cytotoxicity in human SK-MEL-2 cells by SRB assay
|
[PMID: 26812172] |
| SK-OV-3 | IC50 |
>10 μM
Compound: 20
|
Cytotoxicity in human SKOV3 cells by SRB assay
Cytotoxicity in human SKOV3 cells by SRB assay
|
[PMID: 26812172] |
Chemical Information
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CAS. Nr. 54113-95-0
-
Molecular Weight 316.43
-
Formel C20H28O3
-
SMILES
O=C([C@]1(C)CCC[C@]2(C)C3=C(CC[C@@]12[H])C=C(C(O)(C)C)C=C3)O
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Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)