15-Hydroxydehydroabietic acid
15-Hydroxydehydroabietic acid is a diterpene compound isolated from the leaves of armand pine.
For research use only. We do not sell to patients.
- CAS No.: 54113-95-0
- Formula: C20H28O3
- Molecular Weight:316.43
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Size
Price
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
15-Hydroxydehydroabietic acid is a diterpene compound isolated from the leaves of armand pine[1].
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
>10 μM
Compound: 20
|
Cytotoxicity in human A549 cells by SRB assay
Cytotoxicity in human A549 cells by SRB assay
|
[PMID: 26812172] |
| HCT-116 | IC50 |
>10 μM
Compound: 20
|
Cytotoxicity in human HCT116 cells by SRB assay
Cytotoxicity in human HCT116 cells by SRB assay
|
[PMID: 26812172] |
| HEK293 | IC50 |
>100 μg/mL
Compound: 32
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Inhibition of TNF-alpha-induced NF-kappaB activity in human pNF-kappaB-luc-293 cells
Inhibition of TNF-alpha-induced NF-kappaB activity in human pNF-kappaB-luc-293 cells
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[PMID: 20022253] |
| LoVo | IC50 |
>25 μg/mL
Compound: 32
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Antiproliferative activity against human LoVo cells
Antiproliferative activity against human LoVo cells
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[PMID: 20022253] |
| QGY-7703 | IC50 |
>25 μg/mL
Compound: 32
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Antiproliferative activity against human QGY7703 cells
Antiproliferative activity against human QGY7703 cells
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[PMID: 20022253] |
| RAW264.7 | IC50 |
76.4 μg/mL
Compound: 32
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Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO release
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced NO release
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[PMID: 20022253] |
| SK-MEL-2 | IC50 |
>10 μM
Compound: 20
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Cytotoxicity in human SK-MEL-2 cells by SRB assay
Cytotoxicity in human SK-MEL-2 cells by SRB assay
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[PMID: 26812172] |
| SK-OV-3 | IC50 |
>10 μM
Compound: 20
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Cytotoxicity in human SKOV3 cells by SRB assay
Cytotoxicity in human SKOV3 cells by SRB assay
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[PMID: 26812172] |
Chemical Information
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CAS No. 54113-95-0
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Molecular Weight 316.43
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Formula C20H28O3
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SMILES
O=C([C@]1(C)CCC[C@]2(C)C3=C(CC[C@@]12[H])C=C(C(O)(C)C)C=C3)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Select Batch:
Purity:
99.98%
Assay:
99.98%
ee.:
99.98%
References
Calculators
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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
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Dilution Calculator
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