19α-Hydroxyasiatic acid
Based on 1 Customer Validation
19α-Hydroxyasiatic acid, a natural triterpenoid, possesses anti-elastase activity.
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- Reinheit: 99.65%
- CAS. Nr.: 70868-78-9
- Formel: C30H48O6
- Molecular Weight:504.70
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Speicherung:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Biologische Aktivität
Beschreibung
Cellular Effect
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | IC50 |
78.96 μM
Compound: 9
|
Inhibition of LPS-induced NF-kappaB activation in HEK293 cells incubated for 4 hrs prior to LPS challenge measured after 48 hrs by luciferase reporter gene assay
Inhibition of LPS-induced NF-kappaB activation in HEK293 cells incubated for 4 hrs prior to LPS challenge measured after 48 hrs by luciferase reporter gene assay
|
[PMID: 23632365] |
Chemical Information
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CAS. Nr. 70868-78-9
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Appearance Solid
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Molecular Weight 504.70
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Formel C30H48O6
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Color White to off-white
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SMILES
OC([C@]12[C@]([C@](O)([C@@H](CC2)C)C)([H])C3=CC[C@@]([C@@]4([C@@]([C@@](C)([C@H]([C@@H](C4)O)O)CO)([H])CC5)C)([H])[C@]5(C)[C@@]3(CC1)C)=O
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Structure Classification
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Initial Source
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Lösungsmittel & Löslichkeit
In Vitro:
DMSO : 5 mg/mL (9.91 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (273 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.9814 mL | 9.9069 mL | 19.8138 mL | 49.5344 mL |
| 5 mM | 0.3963 mL | 1.9814 mL | 3.9628 mL | 9.9069 mL |