2,6-Dihydroxy-4-methoxyacetophenone
2,6-Dihydroxy-4-methoxyacetophenone is a phytoalexin, that can be isolated from the root tissue of Sanguisorba minor. 2,6-Dihydroxy-4-methoxyacetophenone exhibits antifungal activity. 2,6-Dihydroxy-4-methoxyacetophenone is a strong germination inhibitor on B. cinerea.
For research use only. We do not sell to patients.
- CAS No.: 7507-89-3
- Formula: C9H10O4
- Molecular Weight:182.17
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | IC50 |
200 μM
Compound: 117, ZINC00900185
|
Inhibition of human KLF10 expressed in human HeLa cells assessed as reduction in transcriptional activity after 24 hrs by CACCC-responsive promoter driven TK-luciferase reporter gene assay
Inhibition of human KLF10 expressed in human HeLa cells assessed as reduction in transcriptional activity after 24 hrs by CACCC-responsive promoter driven TK-luciferase reporter gene assay
|
[PMID: 25581017] |
2,6-Dihydroxy-4-methoxyacetophenone exhibits antifungal activity against two non-pathogenic fungi, Botrytis cinerea and Phomopsis perniciosa. The ED50s on spore germination were 45 and 410 μM, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 7507-89-3
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Molecular Weight 182.17
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Formula C9H10O4
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SMILES
CC(C1=C(O)C=C(OC)C=C1O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)