2'-Deoxycytidine-2'-13C
Based on 1 Customer Validation
2'-Deoxycytidine-2'-13C is 13C labeled 2'-Deoxycytidine. 2'-Deoxycytidine, a deoxyribonucleoside, can inhibit biological effects of Bromodeoxyuridine (Brdu). 2'-Deoxycytidine is essential for the synthesis of nucleic acids, that can be used for the research of cancer.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C813CH13N3O4
- 分子量:228.21
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- プロトコル
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
Endogenous Metabolite アイソフォーム固有の製品をすべて表示
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生物活性
製品説明
アプリケーション
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
化学情報
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非標識Cas 951-77-9
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分子量 228.21
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分子式 C813CH13N3O4
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SMILES
O[C@H]1[13CH2][C@H](N2C=CC(N)=NC2=O)O[C@@H]1CO
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別名
Deoxycytidine-13C; Cytosine deoxyriboside-13C; Deoxyribose cytidine-13C
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
溶剤 & 溶解度
体外:
H2O : 50 mg/mL (219.10 mM; Need ultrasonic)
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
純度とドキュメンテーション
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Iwazaki A, et al. Intravenously administered 2'-deoxycytidine suppresses mouse myeloma tumor growth. Biol Pharm Bull. 2012;35(2):251-5. [Content Brief]
[3]. Horn D, et al. Inhibition of biological effects of bromodeoxyuridine by deoxycytidine: correlation with decreased incorporation of bromodeoxyuridine into DNA. Somatic Cell Genet. 1976 Sep;2(5):469-81. [Content Brief]
Complete Stock Solution Preparation Table
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 4.3819 mL | 21.9096 mL | 43.8193 mL | 109.5482 mL |
| 5 mM | 0.8764 mL | 4.3819 mL | 8.7639 mL | 21.9096 mL | |
| 10 mM | 0.4382 mL | 2.1910 mL | 4.3819 mL | 10.9548 mL | |
| 15 mM | 0.2921 mL | 1.4606 mL | 2.9213 mL | 7.3032 mL | |
| 20 mM | 0.2191 mL | 1.0955 mL | 2.1910 mL | 5.4774 mL | |
| 25 mM | 0.1753 mL | 0.8764 mL | 1.7528 mL | 4.3819 mL | |
| 30 mM | 0.1461 mL | 0.7303 mL | 1.4606 mL | 3.6516 mL | |
| 40 mM | 0.1095 mL | 0.5477 mL | 1.0955 mL | 2.7387 mL | |
| 50 mM | 0.0876 mL | 0.4382 mL | 0.8764 mL | 2.1910 mL | |
| 60 mM | 0.0730 mL | 0.3652 mL | 0.7303 mL | 1.8258 mL | |
| 80 mM | 0.0548 mL | 0.2739 mL | 0.5477 mL | 1.3694 mL | |
| 100 mM | 0.0438 mL | 0.2191 mL | 0.4382 mL | 1.0955 mL |
2'-Deoxycytidine-2'-13C 関連分類
HY-W654136 関連分類
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