3′-Bromo-3′-deoxythymidine
3′-Bromo-3′-deoxythymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
For research use only. We do not sell to patients.
- CAS No.: 99785-51-0
- Formula: C11H14BrNO4
- Molecular Weight:304.14
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Huh-7 | CC50 |
>100 μg/mL
Compound: 7
|
Cytotoxicity against human HuH7 cells after 2 days by XTT assay
Cytotoxicity against human HuH7 cells after 2 days by XTT assay
|
[PMID: 20420370] |
| Huh-7 | CC50 |
>100 μg/mL
Compound: 7
|
Cytotoxicity against human HuH7 cells assessed as incorporation of [3H]thymidine into DNA after 2 days by scintillation counting
Cytotoxicity against human HuH7 cells assessed as incorporation of [3H]thymidine into DNA after 2 days by scintillation counting
|
[PMID: 20420370] |
Chemical Information
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CAS No. 99785-51-0
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Molecular Weight 304.14
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Formula C11H14BrNO4
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SMILES
OC[C@@H]1[C@@H](Br)C[C@H](C2C(NC(C(C)=C2)=O)=O)O1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)