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Art. -Nr.: HY-122711

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3-Cyanochromone

Name: 3-Cyanochromone
Brand: MedChemExpress
SKU: HY-122711
Price: 25.00 USD
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Rating: 5 (1 reviews)

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3-Cyanochromone (Compound fragment 1) is a dual NDM-1 and VIM-2 inhibitor with K_D values of 181 μM and 999 μM, respectively. 3-Cyanochromone is promising for research of antibiotics.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

CAS. Nr.: 50743-17-4

Formel: C₁₀H₅NO₂

Molecular Weight:171.16

Speicherung:

Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month

Data Sheet (269 KB)

3-Cyanochromone Chemical Structure

CAS. Nr.: 50743-17-4

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Data Download

Data Sheet (269 KB)

Handling Instructions (2659 KB)

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Finden Sie Ihren Händler vor Ort Your local distributor: Hycultec GmbHHycultec

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Help & FAQs

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Alle Beta-lactamase Isoform-spezifische Produkte anzeigen
More

Metallo-β-lactamase (MBL)

Serine β-lactamase (SBL)

Biologische Aktivität

Beschreibung

IC₅₀ & Target

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

Classifications

Bioz

Biologische Aktivität

Beschreibung

3-Cyanochromone (Compound fragment 1) is a dual NDM-1 and VIM-2 inhibitor with K_D values of 181 μM and 999 μM, respectively. 3-Cyanochromone is promising for research of antibiotics^[1]^[2].

IC₅₀ & Target

NDM-1

181 μM (Kd)

VIM-2

999 μM (Kd)

Alle Beta-lactamase Isoform-spezifische Produkte anzeigen :

Metallo-β-lactamase (MBL)

Serine β-lactamase (SBL)

Chemical Information

CAS. Nr. 50743-17-4

Appearance Solid

Molecular Weight 171.16

Formel C₁₀H₅NO₂

SMILES

N#CC1=COC=2C=CC=CC2C1=O

Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Powder -20°C 3 years

4°C 2 years

In solvent -80°C 6 months

-20°C 1 month

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)

SDS (252 KB)

Français - FR (252 KB)

Deutsch - DE (252 KB)

Norwegian - NO (252 KB)

Español - ES (252 KB)

Swedish - SV (252 KB)

Italian - IT (252 KB)

Korean - KR (252 KB)

Portuguese - PT (252 KB)

COA (2659 KB)

Elemental Analysis Report (2659 KB)

HNMR (2659 KB)

CNMR (2659 KB)

RP-HPLC (2659 KB)

NP-HPLC (2659 KB)

MS (2659 KB)

LCMS (2659 KB)

IR (2659 KB)

GC (2659 KB)

OR (2659 KB)

SDS-PAGE (2659 KB)

SEC-HPLC (2659 KB)

Other Report (2659 KB)

Handling Instructions (2659 KB)

Verweise

[1]. Christopeit T, et al. Fragment-based discovery of inhibitor scaffolds targeting the metallo-β-lactamases NDM-1 and VIM-2. Bioorg Med Chem Lett. 2016 Apr 15;26(8):1973-7. [Content Brief]

[2]. Xiao Q, et al. Silver-catalyzed cascade reactions of 3-cyanochromone with 1, 1-enediamines: synthesis of highly functionalized 2-(pyridin-3-yl)-chromeno [2, 3-d] pyrimidines[J]. Organic Chemistry Frontiers, 2020, 7(15): 2035-2039.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

=
Konzentration Konzentration

×
Volumen Volumen

×
Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

×

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

=

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

×

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

3-Cyanochromone Related Classifications

HY-122711 Related Classifications

Anti-infection

Beta-lactamase

Disease Areas

Infection

Infection

Bioz

Powered by Bioz See more details on Bioz

Keywords

3-Cyanochromone
50743-17-4
Beta-lactamase
NDM-1
VIM-2
antibiotics
Inhibitor
inhibitor
inhibit

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