3β-Hydroxy-27-p-Z-coumaroyloxyurs-12-en-28-oic acid
3β-Hydroxy-27-p-Z-coumaroyloxyurs-12-en-28-oic acid (compound 8) is a triterpenoid ester HIV-1 protease inhibitor with the potential for use in the antiretroviral combination therapy of AIDS.
For research use only. We do not sell to patients.
- Formula: C39H54O6
- Molecular Weight:618.84
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
HIV-1[1]
Cellular Effect
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | IC50 |
6.1 μM
Compound: 11
|
Cytotoxicity against human HeLa cells assessed as reduction in cell viability by MTT assay
Cytotoxicity against human HeLa cells assessed as reduction in cell viability by MTT assay
|
[PMID: 31820973] |
Chemical Information
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Molecular Weight 618.84
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Formula C39H54O6
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SMILES
OC(C=C1)=CC=C1/C=C\C(OC[C@@]23C([C@@]4([H])[C@@](CC3)(CC[C@H]([C@@H]4C)C)C(O)=O)=CC[C@@]5([H])[C@]2(CC[C@]6([H])[C@@]5(CC[C@@H](C6(C)C)O)C)C)=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)