Bisphenol F-13C12
Bisphenol F-13C12 is the 13C labeled Bisphenol F (HY-W014901). Bisphenol F is an orally active endocrine disruptor. Bisphenol F promotes ROS generation, upregulates p-AKT/p-GSK3β, and induces Apoptosis. Bisphenol F interferes with glucose metabolism, affects neurodevelopment and reproductive function. Bisphenol F reduces social novelty preference in mouse offspring. Bisphenol F can be used in bone, blood, and fat-related studies. Bisphenol F is used as a substitute for Bisphenol A (HY-18260).
For research use only. We do not sell to patients.
- CAS No.: 1410794-08-9
- Formula: C13C12H12O2
- Molecular Weight:212.15
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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GSK-3β |
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1410794-08-9
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Unlabeled Cas 620-92-8
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Molecular Weight 212.15
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Formula C13C12H12O2
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SMILES
O[13C]([13CH]=[13CH]1)=[13CH][13CH]=[13C]1C[13C]2=[13CH][13CH]=[13C]([13CH]=[13CH]2)O
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Synonyms
BPF-13C12; 4,4'-Dihydroxydiphenylmethane-13C12
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Huang M, et al. Bisphenol A and its analogues bisphenol S, bisphenol F and bisphenol AF induce oxidative stress and biomacromolecular damage in human granulosa KGN cells. Chemosphere. 2020 Aug;253:126707. [Content Brief]
[2]. García-Recio E, et al. Effects of bisphenol F, bisphenol S, and bisphenol AF on cultured human osteoblasts. Arch Toxicol. 2023 Jul;97(7):1899-1905. [Content Brief]
[3]. Maćczak A, et al. Bisphenol A, bisphenol S, bisphenol F and bisphenol AF induce different oxidative stress and damage in human red blood cells (in vitro study). Toxicol In Vitro. 2017 Jun;41:143-149. [Content Brief]
[4]. Drobna Z, et al. Bisphenol F has different effects on preadipocytes differentiation and weight gain in adult mice as compared with Bisphenol A and S. Toxicology. 2019 May 15;420:66-72. [Content Brief]
[5]. Kim Y, et al. Mechanism of Bisphenol F Affecting Motor System and Motor Activity in Zebrafish. Toxics. 2023 May 24;11(6):477. [Content Brief]
[6]. Li B, et al. Effect of bisphenol F on reproductive function in F1 generation male mice and its potential mechanisms. Environ Pollut. 2025 Feb 15;367:125546. [Content Brief]
[7]. Lv Z, et al. In vivo hypoglycemic effects of bisphenol F exposure in high-fat diet mice. Chemosphere. 2023 Jan;311(Pt 1):137066. [Content Brief]
[8]. Moon HJ, et al. Effects of prenatal bisphenol S and bisphenol F exposure on behavior of offspring mice. Anim Cells Syst (Seoul). 2023 Oct 11;27(1):260-271. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)