4α-Hydroxycholesterol
Based on 1 Customer Validation
4α-Hydroxycholesterol is an isomer of 4β-Hydroxycholesterol (HY-124265). 4α-Hydroxycholesterol has a slight effect on the integrity of lysosomal membranes in mouse primary oligodendrocyte cultures.
For research use only. We do not sell to patients.
- Purity: 99.64%
- CAS No.: 34310-86-6
- Formula: C27H46O2
- Molecular Weight:402.65
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Storage:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| C6 | IC50 |
>=160 μM
Compound: 2, 4alpha-hydroxycholesterol, 4alpha-OHC
|
Cytostatic activity against rat C6 cells assessed as growth inhibition after 24 hrs by trypan blue-based cell counting method
Cytostatic activity against rat C6 cells assessed as growth inhibition after 24 hrs by trypan blue-based cell counting method
|
[PMID: 24211631] |
| C6 | IC50 |
160 μM
Compound: 2, 4alpha-hydroxycholesterol, 4alpha-OHC
|
Cytostatic activity against rat C6 cells assessed as growth inhibition after 24 hrs by trypan blue-based cell counting method
Cytostatic activity against rat C6 cells assessed as growth inhibition after 24 hrs by trypan blue-based cell counting method
|
[PMID: 24211631] |
Chemical Information
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CAS No. 34310-86-6
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Appearance Solid
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Molecular Weight 402.65
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Formula C27H46O2
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Color White to yellow
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SMILES
C[C@@]12[C@]3([H])[C@](CC=C1[C@@H]([C@H](CC2)O)O)([H])[C@@]4([H])[C@](CC3)([C@@](CC4)([H])[C@H](C)CCCC(C)C)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Purity & Documentation
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Data Sheet (266 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)