4-Bromophenylacetonitrile
Based on 1 Customer Validation
4-Bromophenylacetonitrile is a PROTAC linker that can be used in the synthesis of PROTACs.
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- Pureté : 99.94%
- CAS No.: 16532-79-9
- Formule: C8H6BrN
- Masse moléculaire:196.05
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Stockage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
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Help & FAQs
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Activité biologique
Description
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E381 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 16532-79-9
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Appearance Solid
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Masse moléculaire 196.05
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Formule C8H6BrN
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Color White to light brown
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SMILES
N#CCC1=CC=C(Br)C=C1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvant et solubilité
In Vitro:
DMSO : 50 mg/mL (255.04 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (241 KB)
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SDS (480 KB)
- English - EN (480 KB)
- Français - FR (480 KB)
- Deutsch - DE (480 KB)
- Norwegian - NO (480 KB)
- Español - ES (480 KB)
- Swedish - SV (480 KB)
- Italian - IT (480 KB)
- Korean - KR (480 KB)
- Portuguese - PT (480 KB)
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Instruction de manipulation (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.1007 mL | 25.5037 mL | 51.0074 mL | 127.5185 mL |
| 5 mM | 1.0201 mL | 5.1007 mL | 10.2015 mL | 25.5037 mL | |
| 10 mM | 0.5101 mL | 2.5504 mL | 5.1007 mL | 12.7518 mL | |
| 15 mM | 0.3400 mL | 1.7002 mL | 3.4005 mL | 8.5012 mL | |
| 20 mM | 0.2550 mL | 1.2752 mL | 2.5504 mL | 6.3759 mL | |
| 25 mM | 0.2040 mL | 1.0201 mL | 2.0403 mL | 5.1007 mL | |
| 30 mM | 0.1700 mL | 0.8501 mL | 1.7002 mL | 4.2506 mL | |
| 40 mM | 0.1275 mL | 0.6376 mL | 1.2752 mL | 3.1880 mL | |
| 50 mM | 0.1020 mL | 0.5101 mL | 1.0201 mL | 2.5504 mL | |
| 60 mM | 0.0850 mL | 0.4251 mL | 0.8501 mL | 2.1253 mL | |
| 80 mM | 0.0638 mL | 0.3188 mL | 0.6376 mL | 1.5940 mL | |
| 100 mM | 0.0510 mL | 0.2550 mL | 0.5101 mL | 1.2752 mL |
4-Bromophenylacetonitrile Related Classifications
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