5-Hydroxycytidine

Cat. No.: HY-Z15868 Purity: 99.77%: Data Sheet
COA

SDS
Handling Instructions
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5-Hydroxycytidine is the RNA modified nucleoside that can be found in the 23S rRNA of bacteria E. coli. 5-Hydroxycytidine modifies at the C2501 site, exhibits a higher modification level in stationary cells. 5-Hydroxycytidine exhibits a higher modification level in radiation resistant Radius than in E. coli.

For research use only. We do not sell to patients.

5-Hydroxycytidine Chemical Structure

CAS No. : 39638-73-8

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	Get quote	Estimated Time of Arrival: December 31
200 mg	Get quote
500 mg	Get quote

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Purity & Documentation
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Description

Molecular Weight

259.22

Formula

C₉H₁₃N₃O₆

CAS No.

39638-73-8

Appearance

Solid

Color

White to off-white

SMILES

O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N2C(N=C(C(O)=C2)N)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 25 mg/mL (96.44 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.8577 mL	19.2886 mL	38.5773 mL
5 mM	0.7715 mL	3.8577 mL	7.7155 mL
10 mM	0.3858 mL	1.9289 mL	3.8577 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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In Vivo Dissolution Calculator

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Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.77%

Select Batch:

Data Sheet (277 KB) SDS (252 KB)

COA (256 KB) HNMR (170 KB) RP-HPLC (206 KB) MS (68 KB)

Handling Instructions (2659 KB)

References

[1]. Havelund JF, et al., Identification of 5-hydroxycytidine at position 2501 concludes characterization of modified nucleotides in E. coli 23S rRNA. J Mol Biol. 2011 Aug 19;411(3):529-36. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.8577 mL	19.2886 mL	38.5773 mL	96.4432 mL
	5 mM	0.7715 mL	3.8577 mL	7.7155 mL	19.2886 mL
	10 mM	0.3858 mL	1.9289 mL	3.8577 mL	9.6443 mL
	15 mM	0.2572 mL	1.2859 mL	2.5718 mL	6.4295 mL
	20 mM	0.1929 mL	0.9644 mL	1.9289 mL	4.8222 mL
	25 mM	0.1543 mL	0.7715 mL	1.5431 mL	3.8577 mL
	30 mM	0.1286 mL	0.6430 mL	1.2859 mL	3.2148 mL
	40 mM	0.0964 mL	0.4822 mL	0.9644 mL	2.4111 mL
	50 mM	0.0772 mL	0.3858 mL	0.7715 mL	1.9289 mL
	60 mM	0.0643 mL	0.3215 mL	0.6430 mL	1.6074 mL
	80 mM	0.0482 mL	0.2411 mL	0.4822 mL	1.2055 mL