5-Methyl-2-thiouridine
Based on 1 Customer Validation
5-Methyl-2-thiouridine (2-Thio-5-methyluridine) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
For research use only. We do not sell to patients.
- Purity: 99.53%
- CAS No.: 32738-09-3
- Formula: C10H14N2O5S
- Molecular Weight:274.29
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Chemical Information
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CAS No. 32738-09-3
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Appearance Solid
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Molecular Weight 274.29
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Formula C10H14N2O5S
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Color White to off-white
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SMILES
OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N2C(NC(C(C)=C2)=O)=S)O1
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Synonyms
2-Thio-5-methyluridine
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 250 mg/mL (911.44 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.6458 mL | 18.2289 mL | 36.4578 mL | 91.1444 mL |
| 5 mM | 0.7292 mL | 3.6458 mL | 7.2916 mL | 18.2289 mL | |
| 10 mM | 0.3646 mL | 1.8229 mL | 3.6458 mL | 9.1144 mL | |
| 15 mM | 0.2431 mL | 1.2153 mL | 2.4305 mL | 6.0763 mL | |
| 20 mM | 0.1823 mL | 0.9114 mL | 1.8229 mL | 4.5572 mL | |
| 25 mM | 0.1458 mL | 0.7292 mL | 1.4583 mL | 3.6458 mL | |
| 30 mM | 0.1215 mL | 0.6076 mL | 1.2153 mL | 3.0381 mL | |
| 40 mM | 0.0911 mL | 0.4557 mL | 0.9114 mL | 2.2786 mL | |
| 50 mM | 0.0729 mL | 0.3646 mL | 0.7292 mL | 1.8229 mL | |
| 60 mM | 0.0608 mL | 0.3038 mL | 0.6076 mL | 1.5191 mL | |
| 80 mM | 0.0456 mL | 0.2279 mL | 0.4557 mL | 1.1393 mL | |
| 100 mM | 0.0365 mL | 0.1823 mL | 0.3646 mL | 0.9114 mL |
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