6-Carboxy-H2DCFDA
6-Carboxy-H2DCFDA (6-Carboxy-2',7'-dichlorodihydrofluorescein) is a non-fluorescent, cell-permeable intracellular ROS indicator. 6-Carboxy-H2DCFDA undergoes oxidation to highly fluorescent carboxy-dichlorofluorescein (Ex/Em = 488/520 nm).
For research use only. We do not sell to patients.
- CAS No.: 247044-02-6
- Formula: C25H16Cl2O9
- Molecular Weight:531.30
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
6-Carboxy-H2DCFDA (1 μM; 2 h) reliably detects intracellular ROS generation in 4-5 day cultured embryonic chick ventricular cardiomyocytes[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 247044-02-6
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Molecular Weight 531.30
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Formula C25H16Cl2O9
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SMILES
O=C(C1=CC=C(C(C2C3=CC(Cl)=C(C=C3OC4=CC(OC(C)=O)=C(C=C42)Cl)OC(C)=O)=C1)C(O)=O)O
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Synonyms
6-Carboxy-2',7'-dichlorodihydrofluorescein
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
6-Carboxy-H2DCFDA Related Classifications
HY-D3376 Related Classifications
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- 6-Carboxy-H2DCFDA
- 247044-02-6
- 6-Carboxy-2',7'-dichlorodihydrofluorescein
- Fluorescent Dye
- Reactive Oxygen Species (ROS)
- reactive oxygen species
- embryonic chick ventricular cardiomyocytes
- intracellular ROS generation
- oxidative injury
- ginsenoside Rb1
- cardiomyocytes
- carboxy-dichlorofluorescein
- Inhibitor
- inhibitor
- inhibit