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Cat. No.: HY-148301

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6α-Hydroxyestradiol

(Synonyms: 6α-Hydroxy-17β-estradiol)

6α-Hydroxyestradiol, a hydroxyestrogen, is an Estradiol (HY-B0141) metabolite.

For research use only. We do not sell to patients.

CAS No.: 1229-24-9
Formula: C₁₈H₂₄O₃
Molecular Weight:288.38

Storage:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

6α-Hydroxyestradiol Chemical Structure

CAS No.: 1229-24-9

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

6α-Hydroxyestradiol, a hydroxyestrogen, is an Estradiol (HY-B0141) metabolite^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
MCF7	EC₅₀	1.86 M Compound: 22	Growth response in cultures of MCF-7 (human breast cancer cell line) cells Growth response in cultures of MCF-7 (human breast cancer cell line) cells	[PMID: 9357533]
MCF7	EC₅₀	1.86 x 10^-9M Compound: 22	Growth response in cultures of MCF-7 (human breast cancer cell line) cells Growth response in cultures of MCF-7 (human breast cancer cell line) cells	[PMID: 9357533]
MCF7	EC₅₀	1.86E-10 M Compound: 22	Growth response in cultures of MCF-7 (human breast cancer cell line) cells Growth response in cultures of MCF-7 (human breast cancer cell line) cells	[PMID: 9357533]

Chemical Information

CAS No. 1229-24-9
Appearance Solid
Molecular Weight 288.38
Formula C₁₈H₂₄O₃
Color White to off-white
SMILES

C[C@@]12[C@](CC[C@@H]2O)([H])[C@@]3([H])[C@@](CC1)([H])C4=CC=C(O)C=C4[C@H](C3)O
Synonyms

6α-Hydroxy-17β-estradiol
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
SDS (560 KB)
- English - EN (560 KB)
- Français - FR (560 KB)
- Deutsch - DE (560 KB)
- Norwegian - NO (560 KB)
- Español - ES (560 KB)
- Swedish - SV (560 KB)
- Italian - IT (560 KB)
- Korean - KR (560 KB)
- Portuguese - PT (560 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Zhu BT, et, al. Stimulatory effect of cigarette smoking on the 15 alpha-hydroxylation of estradiol by human term placenta. Clin Pharmacol Ther. 2002 May;71(5):311-24. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biological Activity
- Description
Chemical Information
Purity & Documentation
References

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6α-Hydroxyestradiol

Estradiol

Estradiol (Standard)

Ethinylestradiol

Estradiol valerate

Alpha-Estradiol

Ethinylestradiol (Standard)

Estradiol valerate (Standard)

Alpha-Estradiol (Standard)

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

6α-Hydroxyestradiol

Estradiol

Estradiol (Standard)

Ethinylestradiol

Estradiol valerate

Alpha-Estradiol

Ethinylestradiol (Standard)

Estradiol valerate (Standard)

Alpha-Estradiol (Standard)

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

6α-Hydroxyestradiol Related Classifications

HY-148301 Related Classifications