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Cat. No.: HY-12306AR

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8-Bromo-cAMP (Standard)

Name: 8-Bromo-cAMP (Standard)
Brand: MedChemExpress
SKU: HY-12306AR
Availability: PreOrder

(Synonyms: 8-Br-Camp (Standard))

8-Bromo-cAMP (Standard) is the analytical standard of 8-Bromo-cAMP (HY-12306A). This product is intended for research and analytical applications. 8-Bromo-cAMP (8-Br-Camp), a cyclic AMP analog, is an activator of cyclic AMP-dependent protein K_inase (PKA). 8-Bromo-cAMP has anti-proliferative and apoptotic effects against cancer cells.

For research use only. We do not sell to patients.

CAS No.: 23583-48-4
Formula: C₁₀H₁₁BrN₅O₆P
Molecular Weight:408.10

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

8-Bromo-cAMP (Standard) Chemical Structure

CAS No.: 23583-48-4

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Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 23583-48-4
Molecular Weight 408.10
Formula C₁₀H₁₁BrN₅O₆P
SMILES

OP1(O[C@@]2([H])[C@@H](O)[C@@H](O[C@]2([H])CO1)N3C(Br)=NC4=C3N=CN=C4N)=O
Synonyms

8-Br-Camp (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Wang Y, et al. A cyclic AMP analog, 8-Br-cAMP, enhances the induction of pluripotency in human fibroblast cells. Stem Cell Rev. 2011 Jun;7(2):331-41. [Content Brief]

[2]. Wang HM, et al. Dual effects of 8-Br-cAMP on differentiation and apoptosis of human esophageal cancer cell line Eca-109. World J Gastroenterol. 2005 Nov 7;11(41):6538-42. [Content Brief]

[3]. Baek MO, et al. Differential regulation of mTORC1 and mTORC2 is critical for 8-Br-cAMP-induced decidualization. Exp Mol Med. 2018 Oct 30;50(10):1-11. [Content Brief]

[4]. Wang S, et al. Angiogenesis and vasculogenic mimicry are inhibited by 8-Br-cAMP through activation of the cAMP/PKA pathway in colorectal cancer. Onco Targets Ther. 2018 Jul 2;11:3765-3774 [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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